Myocardial lactate extraction: multi-determined metabolic function.
نویسندگان
چکیده
منابع مشابه
Myocardial lactate extraction: multi-determined metabolic function.
Myocardial lactate production indicates anaerobic metabolism resulting from hypoxia or anoxia. Clinically, myocardial lactate extraction of less than 10% has also been used as an indicator of ischemia. Sixteen healthy young male volunteers underwent coronary sinus and aterial catheterization. A coronary sinus pacing catheter was used to obtain blood samples and increase the heart rate to twice ...
متن کاملMetabolic oxidation of pyruvate and lactate during early myocardial reperfusion.
We have previously described the rates of oxidation for long-chain fatty acids and glucose in stunned myocardium during early reflow after moderately severe regional ischemia. The purpose of these studies was to characterize the rates of pyruvate and lactate oxidation during comparable periods of reflow. In the main protocol, pyruvate oxidation was defined at two conditions of coronary flow and...
متن کاملMyocardial lactate metabolism: evidence of lactate release during net chemical extraction in man.
Myocardial blood flow has been recognized to be heterogeneous in patients with coronary artery disease. Traditional arterial-coronary sinus sampling methods cannot demonstrate comparable heterogeneity of myocardial metabolism. In this study we used a tracer technique to investigate possible heterogeneity of myocardial lactate metabolism. Twenty-one patients with symptoms of ischemic heart disea...
متن کاملMetabolic Syndrome, Strain, and Reduced Myocardial Function: Multi-Ethnic Study of Atherosclerosis
BACKGROUND Subclinical cardiovascular disease is prevalent in patients with Metabolic Syndrome (MetSyn). Left ventricular (LV) circumferential strain (εCC) and longitudinal strain (εLL), assessed by Speckle Tracking Echocardiography (STE), are indices of systolic function: shortening is indicated by negative strain, and thus, the more negative the strain, the better the LV systolic function. Th...
متن کاملMetabolic acidosis with discrepant lactate results.
A 40-year-old woman was found unresponsive after a night of ethanol consumption. Her history was significant for alcohol abuse, bipolar disorder, and previous suicide attempts. Respiratory and renal failure occurred soon after hospitalization. Initial laboratory results included the following: blood ethanol, 17 mg/dL [reference interval, 0 or LOQ (limit of quantification)]; pH, 6.98 (7.35–7.45)...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Circulation
سال: 1980
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.61.2.256